Pávek, Petr: search on Z-Library

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1

P-glycoprotein in the placenta: Expression, localization, regulation and function

Martina Ceckova-Novotna, Petr Pavek, Frantisek Staud

Journal:

Reproductive Toxicology

Year:

2006

Language:

english

File:

PDF, 1.07 MB

english, 2006

2

Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene

Lucie Krausova, Lucie Stejskalova, Hongwei Wang, Radim Vrzal, Zdenek Dvorak, Sridhar Mani, Petr Pavek

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 1015 KB

english, 2011

3

Comment on “The role of redox-sensitive transcription factors NF-kB and AP-1 in the modulation of the Cyp1A1 gene by mercury, lead, and copper”

Zdenek Dvorak, Petr Pavek

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

4

Novel cell line for assessment of aryl hydrocarbon receptor transcriptional activity

Aneta Novotna, Zdenek Dvorak, Petr Pavek

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 86 KB

english, 2012

5

Role of breast cancer resistance protein (Bcrp/Abcg2) in fetal protection during gestation in rat

Lenka Cygalova, Martina Ceckova, Petr Pavek, Frantisek Staud

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 329 KB

english, 2008

6

Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines

Radim Vrzal, Katerina Kubesova, Petr Pavek, Zdenek Dvorak

Journal:

Toxicology Letters

Year:

2010

Language:

english

File:

PDF, 525 KB

english, 2010

7

Circulating cytokine pattern and factors describing rheumatoid arthritis: IL-15 as one of the biomarkers for RA?

Pavkova Goldbergova, Monika, Pavek, Nikolas, Lipkova, Jolana, Jarkovsky, Jiri, Stouracova, Martina, Gatterova, Jindra, Vasku, Anna, Soucek, Miroslav, Nemec, Petr

Journal:

Year:

2012

Language:

english

File:

PDF, 994 KB

english, 2012

8

Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 “missing heritability” enigma

Smutny, Tomas, Duintjer Tebbens, Jurjen, Pavek, Petr

Journal:

Journal of Applied Biomedicine

Year:

2015

Language:

english

File:

PDF, 778 KB

english, 2015

9

Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

Carazo, Alejandro, Hyrsova, Lucie, Dusek, Jan, Chodounska, Hana, Horvatova, Alzbeta, Berka, Karel, Bazgier, Vaclav, Gan-Schreier, Hongying, Chamulitrat, Waleé, Kudova, Eva, Pavek, Petr

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 1.25 MB

english, 2016

10

Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation

Dusek, Jan, Carazo, Alejandro, Trejtnar, Frantisek, Hyrsova, Lucie, Holas, Ondřej, Smutny, Tomas, Micuda, Stanislav, Pavek, Petr

Journal:

Food and Chemical Toxicology

Year:

2017

Language:

english

File:

PDF, 2.99 MB

english, 2017

11

Ursodeoxycholyl lysophosphatidylethanolamide negatively regulates TLR-mediated lipopolysaccharide response in human THP-1-derived macrophages

Horvatova, Alzbeta, Utaipan, Tanyarath, Otto, Ann-Christin, Zhang, Yuling, Gan-Schreier, Hongying, Pavek, Petr, Pathil, Anita, Stremmel, Wolfgang, Chamulitrat, Walee

Journal:

European Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 2.59 MB

english, 2018

12

Unexpected effects of propiconazole, tebuconazole and their mixture on the receptors CAR and PXR in human liver cells

Knebel, Constanze, Neeb, Jannika, Zahn, Elisabeth, Schmidt, Flavia, Carazo, Alejandro, Holas, Ondej, Pavek, Petr, Püschel, Gerhard P, Zanger, Ulrich M, Süssmuth, Roderich, Lampen, Alfonso, Marx-Stoelt

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 1.96 MB

english, 2018

13

Fully automatic flow-based device for monitoring of drug permeation across a cell monolayer

Zelená, Lucie, Marques, Sara S., Segundo, Marcela A., Miró, Manuel, Pávek, Petr, Sklenářová, Hana, Solich, Petr

Journal:

Analytical and Bioanalytical Chemistry

Year:

2016

Language:

english

File:

PDF, 1.69 MB

english, 2016

14

Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling

Carazo, Alejandro, Dusek, Jan, Holas, Ondrej, Skoda, Josef, Hyrsova, Lucie, Smutny, Tomas, Soukup, Tomas, Dosedel, Martin, Pávek, Petr

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 5.65 MB

english, 2018

15

Effects of anthocyanins on the AhR–CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines

Kamenickova, Alzbeta, Anzenbacherova, Eva, Pavek, Petr, Soshilov, Anatoly A., Denison, Michael S., Zapletalova, Michaela, Anzenbacher, Pavel, Dvorak, Zdenek

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

16

Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes

Pavek, Petr, Stejskalova, Lucie, Krausova, Lucie, Bitman, Michal, Vrzal, Radim, Dvorak, Zdenek

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 638 KB

english, 2012

17

Correction to: Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter

Navrátilová, Lucie, Applová, Lenka, Horký, Pavel, Mladěnka, Přemysl, Pávek, Petr, Trejtnar, František

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2018

Language:

english

File:

PDF, 284 KB

english, 2018

18

Construction and characterization of hepatocyte nuclear factor HNF4alpha1 over-expressing cell line derived from human hepatoma HepG2 cells

Aneta Novotna, Aneta Doricakova, Radim Vrzal, Petr Pavek, Zdenek Dvorak

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.26 MB

english, 2011

19

1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria

Karabanovich, Galina, Roh, Jaroslav, Smutný, Tomáš, Němeček, Jan, Vicherek, Petr, Stolaříková, Jiřina, Vejsová, Marcela, Dufková, Ida, Vávrová, Kateřina, Pávek, Petr, Klimešová, Věra, Hrabálek, Alexan

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 815 KB

english, 2014

20

The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients

Soukup, Tomas, Dosedel, Martin, Pavek, Petr, Nekvindova, Jana, Barvik, Ivan, Bubancova, Iva, Bradna, Petr, Kubena, Ales Antonin, Carazo, Alejandro Fernández, Veleta, Tomas, Vlcek, Jiri

Journal:

Rheumatology International

Year:

2015

Language:

english

File:

PDF, 392 KB

english, 2015

21

Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter

Navrátilová, Lucie, Applová, Lenka, Horký, Pavel, Mladěnka, Přemysl, Pávek, Petr, Trejtnar, František

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

22

Metformin induces PGC-1α expression and selectively affects hepatic PGC-1α functions

Aatsinki, Sanna-Mari, Buler, Marcin, Salomäki, Henriikka, Koulu, Markku, Pavek, Petr, Hakkola, Jukka

Journal:

British Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

23

Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug–Drug Interactions

Mandíková, Jana, Volková, Marie, Pávek, Petr, Navrátilová, Lucie, Hyršová, Lucie, Janeba, Zlatko, Pavlík, Jan, Bárta, Pavel, Trejtnar, František

Journal:

Frontiers in Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.38 MB

english, 2016

24

P-glycoprotein expression and distribution in the rat placenta during pregnancy

Martina Novotna, Antonin Libra, Martin Kopecky, Petr Pavek, Zdenek Fendrich, Vladimir Semecky, Frantisek Staud

Journal:

Reproductive Toxicology

Year:

2004

Language:

english

File:

PDF, 362 KB

english, 2004

25

Construction and characterization of stable transfected hepatocyte-like cells

Zdenek Dvorak, Petr Pavek, Aneta Novotna

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 86 KB

english, 2012

26

Pregnane X Receptor and Cancer: Context-Specificity is Key

R. Pondugula, Satyanarayana, Pavek, Petr, Mani, Sridhar

Journal:

Nuclear Receptor Research

Year:

2016

Language:

english

File:

PDF, 449 KB

english, 2016

27

Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone

Jakub Hofman, Davoud Ahmadimoghaddam, Lenka Hahnova, Petr Pavek, Martina Ceckova, Frantisek Staud

Journal:

Pharmacological Research

Year:

2012

Language:

english

File:

PDF, 988 KB

english, 2012

28

Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α upregulation in primary human hepatocytes

Rulcova, Alice, Krausova, Lucie, Smutny, Tomas, Vrzal, Radim, Dvorak, Zdenek, Jover, Ramiro, Pavek, Petr

Journal:

Pharmacological Reports

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

29

Construction and characterization of a reporter gene cell line for assessment of human glucocorticoid receptor activation

Novotna, Aneta, Pavek, Petr, Dvorak, Zdenek

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 558 KB

english, 2012

30

Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis

Česnek, Michal, Jansa, Petr, Šmídková, Markéta, Mertlíková-Kaiserová, Helena, Dračínský, Martin, Brust, Tarsis F., Pávek, Petr, Trejtnar, František, Watts, Val J., Janeba, Zlatko

Journal:

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

31

The plausible association of MTHFR and ADORA2A polymorphisms with nodules in rheumatoid arthritis patients treated with methotrexate

Soukup, Tomas, Dosedel, Martin, Nekvindova, Jana, Antonin Kubena, Ales, Tacheci, Ilja, Duintjer Tebbens, Jurjen, Vlcek, Jiri, Bradna, Petr, Barvik, Ivan, Pavek, Petr

Journal:

Pharmacogenetics and Genomics

Year:

2017

Language:

english

File:

PDF, 150 KB

english, 2017

32

Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain

Skoda, Josef, Dusek, Jan, Drastik, Martin, Stefela, Alzbeta, Dohnalova, Klara, Chalupsky, Karel, Smutny, Tomas, Micuda, Stanislav, Gerbal-Chaloin, Sabine, Pavek, Petr

Journal:

Year:

2020

File:

PDF, 2.37 MB

2020

33

Interactions with selected drug renal transporters and transporter-mediated cytotoxicity in antiviral agents from the group of acyclic nucleoside phosphonates

Mandíková, Jana, Volková, Marie, Pávek, Petr, Česnek, Michal, Janeba, Zlatko, Kubíček, Vladimír, Trejtnar, František

Journal:

Year:

2013

Language:

english

File:

PDF, 873 KB

english, 2013

34

Glucocorticoid Receptor Functions in HeLa Cells Are Perturbed by 2,3,8,9-tetrachlorodibenzo-p-dioxin (TCDD)

Vrzal, Radim, Ulrichova, Jitka, Dvorak, Zdenek, Pavek, Petr

Journal:

Drug Metabolism Letters

Year:

2007

Language:

english

File:

PDF, 206 KB

english, 2007

35

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents

Karabanovich, Galina, Němeček, Jan, Valášková, Lenka, Carazo, Alejandro, Konečná, Klára, Stolaříková, Jiřina, Hrabálek, Alexandr, Pavliš, Oto, Pávek, Petr, Vávrová, Kateřina, Roh, Jaroslav, Klimešová,

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.46 MB

english, 2016

36

Modulation of xenobiotic conjugation enzymes by dihydromyricetin in rats

Bebová, Michaela, Boštíková, Zdislava, Moserová, Michaela, Pávek, Petr, Anzenbacherová, Eva, Stiborová, Marie, Hodek, Petr

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

37

Marine Ligands of the Pregnane X Receptor (PXR): An Overview

Carazo, Alejandro, Mladěnka, Přemysl, Pávek, Petr

Journal:

Year:

2019

Language:

english

File:

PDF, 1.77 MB

english, 2019

38

EXPRESSION AND FUNCTIONAL ACTIVITY OF BREAST CANCER RESISTANCE PROTEIN (BCRP, ABCG2) TRANSPORTER IN THE HUMAN CHORIOCARCINOMA CELL LINE BEWO

Martina Ceckova, Antonin Libra, Petr Pavek, Petr Nachtigal, Marianne Brabec, Renate Fuchs, Frantisek Staud

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2006

Language:

english

File:

PDF, 228 KB

english, 2006

39

Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily

Smutny, Tomas, Mani, Sridhar, Pavek, Petr

Journal:

Current Drug Metabolism

Year:

2013

Language:

english

File:

PDF, 454 KB

english, 2013

40

New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase

Jana Malakova, Petr Pavek, Lucie Svecova, Iveta Jokesova, Pavel Zivny, Vladimir Palicka

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 282 KB

english, 2009

41

The role of residues T248, Y249 and T422 in the function of human pregnane X receptor

Aneta Doricakova, Aneta Novotna, Radim Vrzal, Petr Pavek, Zdenek Dvorak

Journal:

Archives of Toxicology

Year:

2013

Language:

english

File:

PDF, 1010 KB

english, 2013

42

Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues

Pavek, Petr, Dvorak, Zdenek

Journal:

Current Drug Metabolism

Year:

2008

Language:

english

File:

PDF, 446 KB

english, 2008

43

Variation of Drug Kinetics in Pregnancy

Pavek, Petr, Ceckova, Martina, Staud, Frantisek

Journal:

Current Drug Metabolism

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

44

3Î²-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3Î±-epimer by hepatic metabolism

Stefela, Alzbeta, Kaspar, Miroslav, Drastik, Martin, Holas, Ondrej, Hroch, Milos, Smutny, Tomas, Skoda, Josef, HutnÃkovÃ¡, Miriama, Pandey, Amit V., Micuda, Stanislav, Kudova, Eva, Pavek, Petr

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2020

File:

PDF, 3.74 MB

2020

45

Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene

Petr Pavek, Katerina Pospechova, Lucie Svecova, Zdenka Syrova, Lucie Stejskalova, Jana Blazkova, Zdenek Dvorak, Jaroslav Blahos

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 657 KB

english, 2010

46

The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids

Smutny, Tomas, Dusek, Jan, Hyrsova, Lucie, Nekvindova, Jana, Horvatova, Alzbeta, Micuda, Stanislav, Gerbal-Chaloin, Sabine, Pavek, Petr

Journal:

Acta Pharmaceutica Sinica B

Year:

2019

Language:

english

File:

PDF, 3.90 MB

english, 2019

47

Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism

Smutny, Tomas, Hyrsova, Lucie, Braeuning, Albert, Ingelman-Sundberg, Magnus, Pavek, Petr

Journal:

Archives of Toxicology

Year:

2020

File:

PDF, 1.47 MB

2020

48

Stereoselective pharmacokinetics of flobufen in rats

Frantisek Trejtnar, Vladimir Wsol, Barbora Szotakova, Lenka Skalova, Petr Pavek, Miroslav Kuchar

Journal:

Year:

1999

Language:

english

File:

PDF, 101 KB

english, 1999

49

The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists

Carazo, Alejandro, Pávek, Petr

Journal:

Year:

2015

Language:

english

File:

PDF, 488 KB

english, 2015

50

Breast cancer resistance protein (BCRP/ABCG2)

Frantisek Staud, Petr Pavek

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

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